Air travel has always played a central role for Gander. The city's location was originally chosen as a refueling depot for flights leaving North America for the United Kingdom and continental Europe, giving it the nickname the "Cross-roads of the world". Its location as the most easterly airport in Canada played an important role in World War II as allied aircraft and troops were stationed in Gander before heading over the Atlantic.
After the war, the town of Gander began to spring up a short distance from the airport. Many of the streets and avenues of Gander are named after historic aviators and airline innovators. Other big names brought to Gander for stop-overs (and longer visits) include Frank Sinatra, Elizabeth Taylor, Jacqueline Kennedy Onassis, The Beatles, Fidel Castro and George Bush Sr.